Research Study · Now Enrolling in New York

The Brain Baseline Study.

We're studying how the healthy adult brain changes over time. Participants receive a personal report on their brain function from both study scans.

Healthy adults 25 to 65 · New York City area · Two MRI scans, at least four months apart

About the Study

What we're studying.

A person in thought, pen in hand Two friends laughing together outdoors A smiling participant in warm light
Purpose

To understand how neuroplasticity, the brain's ability to adapt and reorganize, varies over time in healthy adults.

What we measure

Brain function across major functional networks, using npMRI on a standard 3T MRI scanner.

What's involved

Two short resting MRI scans at least four months apart, plus an optional activity journal between scans.

Where

Partner imaging sites in the New York City area.

Oversight

Conducted under the oversight of an Institutional Review Board (IRB).

How it Works

What taking part looks like.

01 · Check eligibility

Fill out a short screening form.

02 · Review consent

Read the consent form and ask the study team anything before you decide.

03 · First scan

A short resting MRI scan at a partner imaging site.

04 · Your report

Go through your brain function report with a member of the study team.

05 · Second scan

At least four months later, so the study can measure change over time.

What You Receive

What participants receive.

EyeThree brain-architecture reports shown on three phones
Brain Function Report

A report covering each functional network and what it does.

Review Session

Time with a member of the study team to walk through your results.

E3Profile Dashboard

Access to your dashboard and an optional activity journal for the length of the study.

Your report describes patterns of brain function for research purposes. It is not a medical diagnosis and should not be used to make medical decisions. There may be no direct benefit to you from taking part.

Who Can Take Part

Who can participate.

You may be eligible if you:

  • Are 25 to 65 years old
  • Live in or can travel to the New York City area
  • Can give informed consent
  • Are willing to complete two MRI scans and, if you like, an activity log between them

You may not be eligible if you:

  • Have an MRI contraindication, such as metal implants or a pacemaker
  • Have claustrophobia or cannot tolerate MRI
  • Are pregnant or planning a pregnancy during the study
  • Have certain brain health conditions (full criteria in the consent form)
  • Currently use benzodiazepines or cannabis regularly
  • Are taking part in another neuroimaging study
Study Costs

What it costs.

This study is participant-funded. Participants pay a fee of $2,000 per scan to cover study-related costs, including MRI scanning, data processing and analysis, platform access and study administration. You can pay before each scan or for both scans at once. Full cost details are in the consent form.

Placeholder Screening form · fields not yet specified in the copy bank (button target: "SEE IF YOU'RE ELIGIBLE")